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$325,000 Active

126 S Main St, De Soto, MO, 63020

0 ba
Subdivision: None
This is an opportunity to own real estate on the Historical De Soto Main Street. With a train depot in the works to be built in our De Soto Town, this could be the best place for you to put your exiting business or start a new one. Great exposure for most any type of business. Large waiting room and private receptionist area. This building offers 8 possible offices. There's a very large open area for displays, conference, or gathering area. There is a lab area that has a sink and it is so big and roomy you could put in a very nice kitchen. Plenty of counter top and cabinets! There's also a kitchenet. Plenty of storage! 2 commercial restrooms. This property is a must see! Side street parking as well as main street parking. Opportunities await you and your imagination!!! At this time the building is being used as an eye doctor's office. The equipment and business has been sold. The property will be available to close on December 15, 2026 or later. This used to be 2 separate buildings, now it's one large one but possibly be converted back to 2 buildings with 2 separate entrances. This is an as is sale and in as is condition. Listing agent must attend showing until empty. Showings are to be scheduled with the Listing Agent by texting and after the hours of business.

Status: Active · MLS# 26066639 · Listing Courtesy of Heartland Realty

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Facts and features

List Price

$ 325,000

Status

Active

Days on market

0

MLS#

26066639

Bedrooms

0

Full baths

0

Subdivision

None

Municipality

De Soto

County

Jefferson

Property Type

Commercial Sale

Type

Commercial Sale

Additional Information

Property Tax (2025)

$2,033

Recent Nearby Sales in 63020

Last 6 closed homes in this zip.

Address Bd/Ba SqFt List Sold Closed
13942 Springdale Road, De Soto, MO 63020 0/0 -- $300,000 $250,000
83.3% of ask
Nov 12, 2026
621 Boyd Street, De Soto, MO 63020 2/1 855 $1,200 $1,225
102.1% of ask
Nov 11, 2026
310 Donaldson Street, De Soto, MO 63020 2/1 786 $170,000 $170,000
100% of ask
Nov 6, 2026
13489 State Route 21, De Soto, MO 63020 2/2 2,998 $285,000 $265,000
93% of ask
Nov 2, 2026
1797 Wellington Dr.,, Unincorporated, MO 63020 0/0 -- $50,000 $35,000
70% of ask
Nov 2, 2026
4310 Old State Road, De Soto, MO 63020 4/4 2,430 $530,000 $485,000
91.5% of ask
Oct 30, 2026

Price & Listing History

Listed for sale at $325,000
Oct 15, 2026
Current status: Active
As of Oct 16, 2026 · $325,000

Every time this home was on the market

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Most MLS-recorded sales near this home

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